CD2 anticorps

N° du produit ABIN3024312

L’anticorps Souris Monoclonal anti-CD2 a été validé pour FACS, IF, WB et Func. Il convient pour détecter CD2 dans des échantillons de Humain et Cat.

Aperçu rapide pour CD2 anticorps (ABIN3024312)

Antigène: CD2

Reactivité: Humain, Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD2 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Functional Studies (Func)

Clone: HuLy-m1

Détail du produit anti-CD2 anticorps

Purification: Protein G affinity chromatography

Immunogène: Human thymocytes were used as the immunogen for the CD2 antibody.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal dilution of the CD2 antibody should be determined by the researcher.\. Functional Activity (Order SAF formulation),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL, Western blot: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur CD2

Antigène: CD2

Autre désignation: CD2

Sujet: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.