CERK anticorps (Internal Region)

N° du produit ABIN302472

Cet anticorps anti-CERK Polyclonal Lapin (ABIN302472) détecte spécifiquement CERK dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CERK anticorps (Internal Region) (ABIN302472)

Antigène: CERK (Ceramide Kinase (CERK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CERK est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CERK anticorps

Épitope: Internal Region

Specificité: This antibody detects Ceramide Kinase (CERK) at internal domain.

Purification: Immunoaffinity Chromatography

Immunogène: CERK antibody was raised against synthetic peptide from internal domain of human CERK.

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections (20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur CERK

Antigène: CERK (Ceramide Kinase (CERK))

Autre désignation: Ceramide Kinase

Sujet: CERK, which phosphorylates Cer to produce ceramide 1-phosphate (C1P), was initially described as a Ca2+-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in polymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.Synonyms: Acylsphingosine kinase, KIAA1646, LK4, Lipid kinase 4, hCERK

ID gène: 64781

NCBI Accession: NP_073603

UniProt: Q8TCT0