Tyrosinase-Related Protein 1 anticorps

N° du produit ABIN3024976

Cet anticorps anti-Tyrosinase-Related Protein 1 est un anticorps Souris Monoclonal détectant Tyrosinase-Related Protein 1 dans IF, FACS et IHC (p). Adapté pour Humain et Souris.

Aperçu rapide pour Tyrosinase-Related Protein 1 anticorps (ABIN3024976)

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM611

Détail du produit anti-Tyrosinase-Related Protein 1 anticorps

Attributs du produit: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Purification: Protein G affinity chromatography

Immunogène: Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal dilution of the TRP1 antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Tris with 1  mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the TRP1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur Tyrosinase-Related Protein 1

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Autre désignation: TRP1

Sujet: It reacts with a 75  kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.