FTL anticorps (AA 38-165)

N° du produit ABIN3025210

Cet anticorps anti-FTL est un anticorps Souris Monoclonal détectant FTL dans WB, IF, FACS et IHC (p). Adapté pour Humain.

Aperçu rapide pour FTL anticorps (AA 38-165) (ABIN3025210)

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FTL est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FTLC1-1

Détail du produit anti-FTL anticorps

Épitope: AA 38-165

Purification: Protein G affinity chromatography

Immunogène: Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin antibody (light chain specific).

Isotype: IgG2b

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ferritin antibody to be titered up or down for optimal performance.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate Buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.\. Western blot: 1-2 μg/mL,FACS: 0.5-1 μg/10^6 cells,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Ferritin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur FTL

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Autre désignation: Ferritin (Light Chain Specific)

Sujet: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

ID gène: 2512

Pathways: Transition Metal Ion Homeostasis