MLANA anticorps

N° du produit ABIN3025225

Cet anticorps anti-MLANA Monoclonal Souris (Clone SPM342) (ABIN3025225) détecte spécifiquement MLANA dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MLANA anticorps (ABIN3025225)

Antigène: MLANA (Melan A (MLANA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MLANA est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: SPM342

Détail du produit anti-MLANA anticorps

Fonction: Anti-Melan-A Antibody (azide and preservative free)

Aucune reactivité croisée: Souris, Rat (Rattus)

Purification: Protein G affinity chromatography

Immunogène: Recombinant human protein was used as the immunogen for this anti-Melan-A antibody.

Isotype: IgG2b, lambda

Information d'application

Indications d'application: The optimal dilution of the anti-Melan-A antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the anti-Melan-A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur MLANA

Antigène: MLANA (Melan A (MLANA))

Autre désignation: Melan-A

Sujet: Melan-A/MART-1 is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1/Melan-A is present in melanosomes and endoplasmic reticulum. This mAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

UniProt: Q16655