MVP anticorps

N° du produit ABIN3025305

L’anticorps anti-MVP Monoclonal Souris est utilisé pour la détection de MVP dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour MVP anticorps (ABIN3025305)

Antigène: MVP (Major Vault Protein (MVP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MVP est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: 1032

Détail du produit anti-MVP anticorps

Fonction: Major Vault Protein Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: Proteins precipitated from human breast cancer MCF-7 cells were used as the immunogen for the Major Vault Protein antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Major Vault Protein antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Major Vault Protein antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur MVP

Antigène: MVP (Major Vault Protein (MVP))

Autre désignation: Major Vault Protein

Sujet: MVP is required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

UniProt: Q14764