HLA DQ anticorps

N° du produit ABIN3025633

Cet anticorps anti-HLA DQ Monoclonal Souris (Clone SPV-L3) (ABIN3025633) détecte spécifiquement HLA DQ dans FACS et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HLA DQ anticorps (ABIN3025633)

Antigène: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA DQ est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Classe de qualité: Carrier-free

Clone: SPV-L3

Détail du produit anti-HLA DQ anticorps

Fonction: HLA-DQ Antibody (MHC II) (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: The T4-positive CTL clone HG-38 was used as the immunogen for the HLA-DQ antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the HLA-DQ antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the HLA-DQ antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur HLA DQ

Antigène: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Autre désignation: HLA-DQ

Sujet: Recognizes a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

UniProt: P01908