Cytokeratin 19 anticorps (full length)
Aperçu rapide pour Cytokeratin 19 anticorps (full length) (ABIN3025848)
Antigène
Voir toutes Cytokeratin 19 (KRT19) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- full length
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Fonction
- Cytokeratin 19 Antibody Cocktail
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Purification
- Protein G affinity chromatography
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Immunogène
- Recombinant full-length human KRT19 protein was used as the immunogen for the Cytokeratin 19 antibody cocktail.
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Isotype
- IgG1, IgG2a, kappa, lambda
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Indications d'application
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Optimal dilution of the Cytokeratin 19 antibody cocktail should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the Cytokeratin 19 antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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Autre désignation
- Cytokeratin 19
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Sujet
- Recognizes a protein of 40 kDa, identified as cytokeratin-19 (CK19), which is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50 % -60 % of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.
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UniProt
- P08727
Antigène
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