CD46 anticorps

N° du produit ABIN3025892

Cet anticorps Souris Monoclonal détecte spécifiquement CD46 dans FACS et IF. Il présente une réactivité envers Humain et Babouin.

Aperçu rapide pour CD46 anticorps (ABIN3025892)

Antigène: CD46

Reactivité: Humain, Babouin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 169-1-E4-3

Détail du produit anti-CD46 anticorps

Aucune reactivité croisée: Cheval

Purification: Protein G affinity chromatography

Immunogène: Stimulated human leukocytes were used as the immunogen for the CD46 antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal dilution of the CD46 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD46 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur CD46

Antigène: CD46

Autre désignation: CD46

Sujet: Recognizes a protein of 52  kDa-58  kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.

Pathways: Regulation of Actin Filament Polymerization