PLA2G3 anticorps (Internal Region)

N° du produit ABIN302624

L’anticorps anti-PLA2G3 Polyclonal Lapin est utilisé pour la détection de PLA2G3 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour PLA2G3 anticorps (Internal Region) (ABIN302624)

Antigène: PLA2G3 (Phospholipase A2, Group III (PLA2G3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLA2G3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PLA2G3 anticorps

Épitope: Internal Region

Specificité: This antibody detects Group III Secreted Phospholipase A2 (GIII-SPLA2) (PLA2G3) at internal domain.

Purification: Immunoaffinity chromatography

Immunogène: Synthetic peptide - KLH conjugated, internal domain of human

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections (2.5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur PLA2G3

Antigène: PLA2G3 (Phospholipase A2, Group III (PLA2G3))

Autre désignation: PLA2G3 / sPLA2-III

Sujet: Human group III secreted phospholipase A2 belongs to a superfamily of intracellular and secreted enzymes that catalyze the hydrolysis of glycerophospholipids at the sn-2 position to release fatty acids and lysophospholipids. Group III PLA2 enzymes were originally identified in invertebrates such as bees and scorpions. Human group III sPLA2 has been shown to be a calcium dependent enzyme. It consists of a central group III sPLA2 domain flanked by unique N- and C-terminal domains that are proteolytically removed in most tissues. The sPLA2 domain is sufficient for catalytic activity. SPLA2-III is preferentially expressed in the microvascular endothelium of tissues with inflammation, ischemic injury and cancer.Synonyms: Group 3 secretory phospholipase A2, Group III secretory phospholipase A2, Phosphatidylcholine 2-acylhydrolase GIII

ID gène: 50487

NCBI Accession: NP_056530

UniProt: Q9NZ20