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ODC1 anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement ODC1 dans WB, IF, FACS et IHC (p). Il présente une réactivité envers Humain et Rat.
N° du produit ABIN3026477

Aperçu rapide pour ODC1 anticorps (ABIN3026477)

Antigène

Voir toutes ODC1 Anticorps
ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reactivité

  • 115
  • 74
  • 53
  • 15
  • 15
  • 1
  • 1
Humain, Rat

Hôte

  • 69
  • 49
  • 2
Souris

Clonalité

  • 65
  • 55
Monoclonal

Conjugué

  • 49
  • 10
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ODC1 est non-conjugé

Application

  • 100
  • 44
  • 32
  • 26
  • 22
  • 21
  • 20
  • 13
  • 13
  • 13
  • 10
  • 9
  • 4
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

ODC1-485
  • Attributs du produit

    This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

    Purification

    Protein G affinity chromatography

    Immunogène

    Recombinant human ODC-1 protein was used as the immunogen for this antibody.

    Isotype

    IgG1 kappa
  • Indications d'application

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,WB: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2)

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Agent conservateur

    Azide free

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store the ODC-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène

    ODC1 (Ornithine Decarboxylase 1 (ODC1))

    Autre désignation

    ODC-1 / Ornithine Decarboxylase 1

    Sujet

    This antibody recognizes a 53  kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

    ID gène

    4953
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