PERP anticorps

N° du produit ABIN302849

Détail du produit anti-PERP anticorps

Antigène: PERP (TP53 Apoptosis Effector (PERP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PERP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: This antibody reacts to a synthetic peptide corresponding to amino acids near the carboxy terminus of human PERP, which differ from the mouse sequence by three amino acids (7-9).

Purification: DEAE-column chromatography

Immunogène: Synthetic peptide

Information d'application

Indications d'application: Western Blot: 0,5 - 1 μg/mL. Immunohistochemistry: 5 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline, containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.

Détails sur PERP

Antigène: PERP (TP53 Apoptosis Effector (PERP))

Autre désignation: PERP (PERP Produits)

Synonymes: anticorps KCP1, anticorps KRTCAP1, anticorps PIGPC1, anticorps RP3-496H19.1, anticorps THW, anticorps dJ496H19.1, anticorps 1110017A08Rik, anticorps kcp1, anticorps krtcap1, anticorps pigpc1, anticorps thw, anticorps fk24g11, anticorps wu:fk24g11, anticorps PERP, anticorps PERP, TP53 apoptosis effector, anticorps PERP, TP53 apoptosis effector S homeolog, anticorps PERP, anticorps Perp, anticorps perp.S, anticorps perp

Sujet: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.Synonyms: KCP-1, KCP1, KRTCAP1, Keratinocyte-associated protein 1, P53-induced protein PIGPC1, PERP, PIGPC1, THW, Transmembrane protein THW, p53 apoptosis effector related to PMP-22

ID gène: 64065

NCBI Accession: NP_071404

UniProt: Q96FX8

Pathways: Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity