TCP1 alpha/CCTA anticorps (AA 311-680)

N° du produit ABIN3029088

Cet anticorps anti-TCP1 alpha/CCTA est un anticorps Lapin Polyclonal détectant TCP1 alpha/CCTA dans WB, ICC et IHC (p). Adapté pour Humain.

Aperçu rapide pour TCP1 alpha/CCTA anticorps (AA 311-680) (ABIN3029088)

Antigène: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCP1 alpha/CCTA est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TCP1 alpha/CCTA anticorps

Épitope: AA 311-680

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 311-680) was used as the immunogen for this p63 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the p63 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the p63 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur TCP1 alpha/CCTA

Antigène: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Autre désignation: p63

Sujet: Tumor protein p63 (TP63), also known as TP73L is a protein that in humans is encoded by the TP63 gene. It is a member of the p53 family of transcription factors. This gene encodes for two main isoforms by alternative promoters (TAp63 and dNp63). TP63 has been mostly restricted to its apoptotic function and more recently as the guardian of oocyte integrity. It has been found that the combined loss of TP63 and p73 results in the failure of cells containing functional p53 to undergo apoptosis in response to DNA damage. It is an essential regulator of stem cell maintenance in stratified epithelial tissues. TP63 is also critical for maintaining the progenitor-cell populations that are necessary to sustain epithelial development and morphogenesis.

UniProt: Q9H3D4