Cet anticorps Lapin Polyclonal détecte spécifiquement TIMP4 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.
The stated application concentrations are suggested starting amounts. Titration of the TIMP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
Store the TIMP4 antibody at -20oC.
Antigène
TIMP4
(TIMP Metallopeptidase Inhibitor 4 (TIMP4))
Autre désignation
TIMP4
Sujet
The tissue inhibitors of metalloproteinases (TIMPs) inhibit matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. The TIMP4 gene contains 5 exons that span 6 kb of genomic DNA. The gene is expressed as a 1.4-kb transcript abundant in heart and present at low levels in several other tissues. expressed TIMP4 inhibits MMPs in vitro. TIMP4 binds both progelatinase A and the C domain in a similar manner to that of TIMP-2.