TIMP4
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
The stated application concentrations are suggested starting amounts. Titration of the TIMP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.2 mg/mL in 1X PBS with 50 % glycerol and 0.025 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
anticorps TIMP4, anticorps TIMP-4, anticorps timp4, anticorps TIMP metallopeptidase inhibitor 4, anticorps TIMP metallopeptidase inhibitor 4, tandem duplicate 3, anticorps tissue inhibitor of metalloproteinase 4, anticorps TIMP4, anticorps timp4.3, anticorps Timp4
Sujet
The tissue inhibitors of metalloproteinases(TIMPs) inhibit matrix metalloproteinases(MMPs), a group of peptidases involved in degradation of the extracellular matrix. The TIMP4 gene contains 5 exons that span 6 kb of genomic DNA. The gene is expressed as a 1.4-kb transcript abundant in heart and present at low levels in several other tissues. expressed TIMP4 inhibits MMPs in vitro. TIMP4 binds both progelatinase A and the C domain in a similar manner to that of TIMP-2.