Alkaline Phosphatase anticorps (AA 21-35)
Aperçu rapide pour Alkaline Phosphatase anticorps (AA 21-35) (ABIN3029904)
Antigène
Voir toutes Alkaline Phosphatase (ALP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-35
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Fonction
- Alkaline Phosphatase Antibody (tissue-nonspecific)
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Séquence
- EKEKDPKYWR DQAQE
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Purification
- Antigen affinity
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Immunogène
- Amino acids 21-35 (EKEKDPKYWRDQAQE) from human ALPL were used as the immunogen for this tissue-nonspecific Alkaline Phosphatase antibody.
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Isotype
- IgG
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Indications d'application
- Titration of the Alkaline Phosphatase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- The lyophilized Alkaline Phosphatase antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Alkaline Phosphatase (ALP)
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Autre désignation
- Alkaline Phosphatase
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Sujet
- Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. Liver/bone/kidney alkaline phosphatase, known as tissue-nonspecific, acts physiologically as a lipid-anchored phosphoethanolamine (PEA) and pyridoxal-5-prime-phosphate (PLP) ectophosphatase. Mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects.
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UniProt
- P05186
Antigène
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