Liver Arginase anticorps (AA 307-323)

N° du produit ABIN3030018

Cet anticorps anti-Liver Arginase est un anticorps Lapin Polyclonal détectant Liver Arginase dans WB. Adapté pour Rat et Souris.

Aperçu rapide pour Liver Arginase anticorps (AA 307-323) (ABIN3030018)

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Liver Arginase est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Liver Arginase anticorps

Épitope: AA 307-323

Purification: Antigen affinity

Immunogène: Amino acids 307-323 (KREGNHKPETDYLKPPK-rat) were used as the immunogen for this Arginase 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Arginase 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Arginase 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Liver Arginase

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Autre désignation: Arginase 1

Sujet: Arginase is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. The isoform encoded by ARG1, referred to as the liver, or A-I, isoform, contributes 98 % of the arginase activity in liver but is also present in red cells. Using a rat ARG1 cDNA clone to probe a human liver cDNA library, Haraguchi et al.(1987) isolated and characterized a cDNA corresponding to the gene. By immunologic studies, 90 % of the arginase in red blood cells and liver was precipitated by an Arginase 1 antibody, whereas only 50 % of the arginase in kidney, brain, and the gastrointestinal tract reacted with it. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P07824

Pathways: Cellular Response to Molecule of Bacterial Origin