BRSK1 anticorps

N° du produit ABIN303016

Détail du produit anti-BRSK1 anticorps

Antigène: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRSK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody reacts to a 28 amino acid peptide from near the carboxy terminus of BRSK1.

Purification: Purified

Immunogène: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Western blot. Immunohistochemistry on paraffin sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline, containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Références pour anticorps anti-BRSK1 (ABIN303016)

Zempel, Thies, Mandelkow, Mandelkow: "Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 36, pp. 11938-50, (2010) (PubMed).

Détails sur BRSK1

Antigène: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Autre désignation: BRSK1 (BRSK1 Produits)

Synonymes: anticorps BRSK1, anticorps hSAD1, anticorps Gm1100, anticorps SAD-B, anticorps SADB, anticorps RGD1563268, anticorps Sad-b, anticorps BR serine/threonine kinase 1, anticorps BRSK1, anticorps Brsk1

Sujet: BRSK1 is thought to be involved in the regulation of G2/M arrest and to function as a checkpoint kinase following DNA damage induced by UV or methyl methane sulfonate. BRSK1 phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.Synonyms: BR serine/threonine-protein kinase 1, KIAA1811, SAD-B, SAD1, SAD1 kinase, Serine/threonine kinase SAD-B

ID gène: 84446

NCBI Accession: NP_115806

UniProt: Q8TDC3