CEBPB anticorps (AA 1-200)

N° du produit ABIN3030344

L’anticorps anti-CEBPB Polyclonal Lapin est utilisé pour la détection de CEBPB dans des échantillons de Humain. Il a été validé pour WB, IF, FACS et IHC (p).

Aperçu rapide pour CEBPB anticorps (AA 1-200) (ABIN3030344)

Antigène: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEBPB est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CEBPB anticorps

Épitope: AA 1-200

Fonction: C/EBP beta Antibody

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 1-200) was used as the immunogen for this C/EBP beta antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the C/EBP beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the C/EBP beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CEBPB

Antigène: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Autre désignation: C/EBP beta

Sujet: CCAAT/enhancer-binding protein beta, also known as is C/EBP beta, is a protein that in humans is encoded by the CEBPB gene. The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the< a href=../search_result.php?search_txt=il-6>IL-6gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. C/EBP beta is critical for normal macrophage functioning, an important immune cell sub-type. Observational work has shown that expression of C/EBP beta in blood leukocytes is positively associated with muscle strength in humans, emphasizing the importance of the immune system, and particularly macrophages, in the maintenance of muscle function.

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation