Claudin 5 anticorps (AA 191-218)
Aperçu rapide pour Claudin 5 anticorps (AA 191-218) (ABIN3030536)
Antigène
Voir toutes Claudin 5 (CLDN5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 191-218
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Purification
- Antigen affinity
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Immunogène
- Amino acids 191-218 (RPDLSFPVKYSAPRRPTATGDYDKKNYV-human) were used as the immunogen for the Claudin-5 antibody.
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Isotype
- IgG
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the Claudin 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- -20 °C
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Stockage commentaire
- After reconstitution, the Claudin 5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Claudin 5 (CLDN5)
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Autre désignation
- Claudin 5
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Sujet
- Claudin-5, also known as BEC1, is a protein that in humans is encoded by the CLDN5 gene. By use of yeast artificial chromosomes, Claudin-5 is localized between polymorphic markers D22S944 and D22S941 on chromosome 22q11, both of which are deleted in more than 80 % of VCFS patients. This gene encodes a member of the claudin family. Family members are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Additionally, it plays a major role in tight junction-specific obliteration of the intercellular space.
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ID gène
- 7122
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Pathways
- Hepatitis C
Antigène
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