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Desmoglein 3 anticorps (AA 981-999)

DSG3 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3030722
  • Antigène Voir toutes Desmoglein 3 (DSG3) Anticorps
    Desmoglein 3 (DSG3)
    Épitope
    • 15
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 981-999
    Reactivité
    • 66
    • 21
    • 16
    Humain
    Hôte
    • 60
    • 26
    Lapin
    Clonalité
    • 59
    • 27
    Polyclonal
    Conjugué
    • 35
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Desmoglein 3 est non-conjugé
    Application
    • 63
    • 35
    • 20
    • 18
    • 16
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogène
    Amino acids 981-999 (QLRGSHTMLCTEDPCSRLI-human ) were used as the immunogen for this Desmoglein 3 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product DSG3 Anticorps primaire
  • Indications d'application
    The stated application concentrations are suggested starting amounts. Titration of the Desmoglein 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the Desmoglein 3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    Desmoglein 3 (DSG3)
    Autre désignation
    Desmoglein 3 (DSG3 Produits)
    Synonymes
    anticorps DSG3, anticorps CDHF6, anticorps PVA, anticorps bal, anticorps balding, anticorps desmoglein 3, anticorps DSG3, anticorps Dsg3
    Sujet
    Desmoglein 3 is also known as PVA (Pemphigus Vulgaris Antigen). Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune diseases of the skin which have as target antigens two different members of the desmoglein subfamily of the desmosomal cadherins: pemphigus vulgaris antigen (PVA, or Desmoglein 3) in the case of PV and Desmoglein 1 in the case of PF. The DSG3 gene, like the genes for DSG1 and DSG2, is located on chromosome 18. The human DSG3 gene consists of 15 exons and spans more than 23 kb. DSG3 and DSG1 are the autoantigens of pemphigus vulgaris and pemphigus foliaceus, respectively. DSG3 and DSG1 are the target antigens in PNP, and IgG autoantibodies against DSG3 in PNP sera play a pathogenic role in the loss of keratinocyte adhesion and blistering.
    UniProt
    P32926
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