Dopamine Receptor d1 anticorps (AA 221-242)

N° du produit ABIN3030766

Cet anticorps Lapin Polyclonal détecte spécifiquement Dopamine Receptor d1 dans WB et IHC (p). Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour Dopamine Receptor d1 anticorps (AA 221-242) (ABIN3030766)

Antigène: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dopamine Receptor d1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Dopamine Receptor d1 anticorps

Épitope: AA 221-242

Purification: Antigen affinity

Immunogène: Amino acids 221-242 (AQKQIRRIAALERAAVHAKNCQ-human) were used as the immunogen for this DRD1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Titration of the Dopamine Receptor D1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: The DRD1 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.

Détails sur Dopamine Receptor d1

Antigène: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Autre désignation: DRD1 Dopamine Receptor D1

Sujet: Dopamine receptor D1 is the most highly expressed DA receptor subtype among the DA receptor family. Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G (or guanine nucleotide-binding) proteins. D2Rs inhibit adenylyl cyclase, but D1Rs stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. DRD1/2 are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1Rs regulate neuron growth and differentiation, influence behaviour and modify DRD2-mediated events. And the presence of a DRD1 gene restriction fragment length polymorphism will be helpful for future disease linkage studies. This protein also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity.

UniProt: P21728

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity