HYAL2 anticorps (AA 142-157)

N° du produit ABIN3031264

Cet anticorps Lapin Polyclonal détecte spécifiquement HYAL2 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour HYAL2 anticorps (AA 142-157) (ABIN3031264)

Antigène: HYAL2 (Hyaluronidase-2 (HYAL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HYAL2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HYAL2 anticorps

Épitope: AA 142-157

Purification: Antigen affinity

Immunogène: Amino acids 142-157 (VRNWQDKDVYRRLSRQ-human) were used as the immunogen for this HYAL2 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the HYAL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the HYAL2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur HYAL2

Antigène: HYAL2 (Hyaluronidase-2 (HYAL2))

Autre désignation: HYAL2

Sujet: Hyaluronoglucosaminidase 2, also known as hyaluronidase 2, and LuCa-2, is an enzyme that in humans is encoded by the HYAL2 gene. HYAL2 cDNAs encode a preprotein with an N-terminal signal peptide. Northern blot analysis indicated that the gene was expressed in all human tissues tested except adult brain, and Western blot analysis detected the protein in all mouse tissues examined except adult brain. HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored protein on the cell surface and serves as a receptor for entry into the cell of the jaagsiekte sheep retrovirus (JSRV). The findings of Rai et al.(2001) that HYAL2 is a GPI-anchored protein on the cell surface showed that GFP would likely be cleaved from HYAL2 during GPI addition, leaving HYAL2 on the cell surface and resulting in GFP transit to the lysosome for degradation.

UniProt: Q12891

Pathways: Transition Metal Ion Homeostasis, Glycosaminoglycan Metabolic Process