CARD9 anticorps (AA 521-536)

N° du produit ABIN303199

Détail du produit anti-CARD9 anticorps

Antigène: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Épitope: AA 521-536

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Séquence: DRENTTGSDN TDTEGS

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide - KLH conjugated corresponding to Amino Acids 521-536 of Human CARD9. The sequence is different from that of Rat origin by two Amino Acids.

Information d'application

Indications d'application: Western Blot (0.5-1 μg/mL). Immunocytochemistry. Immunohistochemistry on Paraffin Sections (10 μg/mL). This antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody LS-D1, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer. Dilute only prior to immediate use.

Détails sur CARD9

Antigène: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Autre désignation: CARD9 (CARD9 Produits)

Synonymes: anticorps Gm782, anticorps card9, anticorps CANDF2, anticorps hCARD9, anticorps caspase recruitment domain family, member 9, anticorps caspase recruitment domain family member 9, anticorps Card9, anticorps CARD9, anticorps card9

Sujet: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-kB. CARD9 is an upstream activator of BCL-10 and NF-kB signaling.Synonyms: Caspase recruitment domain-containing protein 9

ID gène: 64170

NCBI Accession: NP_434700

UniProt: Q9H257

Pathways: Activation of Innate immune Response