RAB3A anticorps (AA 192-220)

N° du produit ABIN3032423

Détail du produit anti-RAB3A anticorps

Antigène: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Épitope: AA 192-220

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB3A est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Amino acids 192-220 (DTADPAVTGAKQGPQLSDQQVPPHQDCAC-human) were used as the immunogen for this Rab3A antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Rab3A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Rab3A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur RAB3A

Antigène: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Autre désignation: Rab3A (RAB3A Produits)

Synonymes: anticorps RAB3, anticorps rab3a, anticorps zgc:92276, anticorps RAB3A, anticorps rab-3a, anticorps si:ch211-255d18.4, anticorps zgc:112516, anticorps RAB3A, member RAS oncogene family, anticorps RAB3A, member RAS oncogene family, a, anticorps RAB3A, member RAS oncogene family L homeolog, anticorps RAB3A, member RAS oncogene family, b, anticorps RAB3A, anticorps Rab3a, anticorps rab3aa, anticorps rab3a.L, anticorps rab3a, anticorps rab3ab

Sujet: Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. Synapsin I stimulated the Rab3A cycle by increasing GTP binding, GTPase activity, and Rab3A recruitment to the synaptic vesicle membrane. Conversely, Rab3A inhibited Synapsin I binding to actin and Synapsin I-induced synaptic vesicle clustering. It has been found that the protein is necessary for both forms of synaptic plasticity, and it is also involved in calcium exocytosis in neurons. In addition to that, Rab3A has been found to regulate a late step in synaptic vesicle fusion.

ID gène: 5864

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport