SH3GLB1 anticorps (C-Term)

N° du produit ABIN303245

L’anticorps Lapin Polyclonal anti-SH3GLB1 a été validé pour WB, IF et IHC (p). Il convient pour détecter SH3GLB1 dans des échantillons de Humain et Souris.

Aperçu rapide pour SH3GLB1 anticorps (C-Term) (ABIN303245)

Antigène: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3GLB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SH3GLB1 anticorps

Épitope: C-Term

Purification: Purified

Immunogène: Synthetic Peptide corresponding to 15 Amino Acid peptide from near the carboxy terminus of human BIF.

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Immunocytochemistry. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.

Détails sur SH3GLB1

Antigène: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Autre désignation: Endophilin-B1

Sujet: BIF-1 contains a Src homology 3 (SH3) domain in the C-terminus. It does not contain any of the conserved Bcl-2 homology (BH) domains of the Bcl-2 family proteins. Human Bif-1 protein shares 96 % and 42 % identity at the amino acids level with mouse and C. elegans, respectively. Overexpression of Bif-1 in transfected cell lines promotes Bax conformational change, caspase activation, and apoptotic cell death following growth factor withdrawal. Bif-1 RNA is abundantly expressed in heart, skeletal muscle, kidney, and placenta.Synonyms: BIF1, Bax-interacting factor 1, Bif-1, KIAA0491, SH3 domain-containing GRB2-like protein B1, SH3GLB1

ID gène: 51100

NCBI Accession: NP_001193580

UniProt: Q9Y371

Pathways: Autophagy