Ectodysplasin A2 Receptor anticorps
Aperçu rapide pour Ectodysplasin A2 Receptor anticorps (ABIN303257)
Antigène
Voir toutes Ectodysplasin A2 Receptor (EDA2R) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody reacts to Human EDA2R, antibody does not detect mouse EDA2R.
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Purification
- Purified
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Immunogène
- Recombinant human EDA2R
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Indications d'application
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Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Ectodysplasin A2 Receptor (EDA2R)
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Autre désignation
- EDA2R / TNFRSF27
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Sujet
- EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support.Synonyms: EDA-A2 receptor, Tumor necrosis factor receptor superfamily member 27, UNQ2448/PRO5727/PRO34080, X-linked ectodysplasin-A2 receptor, XEDAR
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ID gène
- 60401
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NCBI Accession
- NP_001186616
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UniProt
- Q9HAV5
Antigène
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