SLC22A6 anticorps (AA 534-550)

N° du produit ABIN3032684

L’anticorps Lapin Polyclonal anti-SLC22A6 a été validé pour WB et IHC (p). Il convient pour détecter SLC22A6 dans des échantillons de Humain et Rat.

Aperçu rapide pour SLC22A6 anticorps (AA 534-550) (ABIN3032684)

Antigène: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC22A6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SLC22A6 anticorps

Épitope: AA 534-550

Purification: Antigen affinity

Immunogène: Amino acids 534-550 (QKYMVPLQASAQEKNGL-human) were used as the immunogen for this SLC22A6 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the SLC22A6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the SLC22A6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur SLC22A6

Antigène: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Autre désignation: SLC22A6

Sujet: Solute carrier family 22 (organic anion transporter), member 6, also called OAT1 or PAHT, is a protein that in humans is encoded by the SLC22A6 gene, which is also a member of the organic anion transporter (OAT) family of proteins. It is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells of the kidneys. It plays a central role in renal organic anion transport. Along with OAT3, OAT1/SLC22A6 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys. The protein functions as organic anion exchanger. When the uptake of one molecule of an organic anion is transported into a cell by an SLC22A6 exchanger, one molecule of an endogenous dicarboxylic acid(such as glutarate, ketoglutarate, etc) is simultaneously transported out of the cell.

UniProt: Q4U2R8

Pathways: Dicarboxylic Acid Transport