STRA8 anticorps (AA 341-355)
Aperçu rapide pour STRA8 anticorps (AA 341-355) (ABIN3032753)
Antigène
Voir toutes STRA8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 341-355
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Fonction
- Stra8 Antibody
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Purification
- Antigen affinity
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Immunogène
- Amino acids 341-355 (DDDVMLLKCLETFDD-rat) were used as the immunogen for this Stra8 antibody.
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Isotype
- IgG
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Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the Stra8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Stra8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- STRA8 (Stimulated By Retinoic Acid 8 (STRA8))
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Autre désignation
- Stra8
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Sujet
- Stimulated by retinoic acid 8 is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid (RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.
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UniProt
- D4ADQ4
Antigène
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