CD27 anticorps (APC)
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- Antigène Voir toutes CD27 Anticorps
- CD27 (CD27 Molecule (CD27))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD27 est conjugé à/à la APC
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Application
- Flow Cytometry (FACS)
- Specificité
- This antibody reacts with CD27 (T14), a 50-55 kDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells.
- Purification
- Size-exclusion chromatography
- Immunogène
- Human peripheral blood lymphocytes
- Clone
- LT27
- Isotype
- IgG2a
- Top Product
- Discover our top product CD27 Anticorps primaire
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- Indications d'application
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Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Dilute only prior to immediate use
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
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- Antigène
- CD27 (CD27 Molecule (CD27))
- Autre désignation
- CD27 (CD27 Produits)
- Synonymes
- anticorps TNFRSF7, anticorps S152, anticorps Tnfrsf7, anticorps Tp55, anticorps S152. LPFS2, anticorps T14, anticorps CD27 molecule, anticorps CD27 antigen, anticorps CD27, anticorps Cd27
- Sujet
- CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7
- ID gène
- 939
- NCBI Accession
- NP_001233
- UniProt
- P26842
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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