Unc5c anticorps (C-Term)

N° du produit ABIN3042323

L’anticorps Lapin Polyclonal anti-Unc5c a été validé pour WB et FACS. Il convient pour détecter Unc5c dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Unc5c anticorps (C-Term) (ABIN3042323)

Antigène: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Unc5c est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-Unc5c anticorps

Épitope: AA 894-930, C-Term

Fonction: Anti-UNC5C Antibody Picoband®

Séquence: DLWEAQNFPD GNLSMLAAVL EEMGRHETVV SLAAEGQ

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-UNC5C Antibody Picoband® (ABIN3042323). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human UNC5C, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
1. "Entrez Gene: UNC5C unc-5 homolog C (C. elegans)". 2. Ackerman SL, Knowles BB (Dec 1998). "Cloning and mapping of the UNC5C gene to human chromosome 4q21-q23".Genomics 52 (2): 205-8. 3. Leonardo ED, Hinck L, Masu M, Keino-Masu K, Ackerman SL, Tessier-Lavigne M (May 1997). "Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors". Nature 386 (6627): 833-8.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Unc5c

Antigène: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Autre désignation: UNC5C

Sujet:

Synonyms: Netrin receptor UNC5C,Protein unc-5 homolog 3,Protein unc-5 homolog C,UNC5C,UNC5H3,

Tissue Specificity: Mainly expressed in brain. Also expressed in kidney. Not expressed in developing or adult lung. .

Background: Netrin receptor UNC5C is a protein that in humans is encoded by the UNC5C gene. This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediates the repellent response to netrin, they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.

Poids moléculaire: 115 kDa

ID gène: 8633

UniProt: O95185