HDAC7 anticorps (N-Term)

N° du produit ABIN3042441

Cet anticorps anti-HDAC7 est un anticorps Lapin Polyclonal détectant HDAC7 dans WB. Adapté pour Humain et Rat.

Aperçu rapide pour HDAC7 anticorps (N-Term) (ABIN3042441)

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HDAC7 anticorps

Épitope: AA 68-103, N-Term

Fonction: Anti-HDAC7 Antibody Picoband®

Séquence: QLLHKDKSKR SAVASSVVKQ KLAEVILKKQ QAALER

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-HDAC7 Antibody Picoband® (ABIN3042441). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC7, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: HDAC7A histone deacetylase 7A". 2. Kao HY, Downes M, Ordentlich P, Evans RM (Jan 2000). "Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression". Genes & Development 14 (1): 55-66. 3. Marks PA, Richon VM, Rifkind RA (Aug 2000). "Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells". Journal of the National Cancer Institute 92 (15): 1210-6.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur HDAC7

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Autre désignation: HDAC7

Sujet:

Synonyms: Histone deacetylase 7,HD7,3.5.1.98,Histone deacetylase 7A,HD7a,HDAC7,HDAC7A,

Tissue Specificity: Liver.

Background: Histone deacetylase 7 is an enzyme that in humans is encoded by the HDAC7 gene. It is mapped to 12q13.1. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation / deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Poids moléculaire: 103 kDa

ID gène: 51564

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development