HNF1A anticorps (AA 431-631)

N° du produit ABIN3042451

Détail du produit anti-HNF1A anticorps

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Épitope: AA 431-631

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF1A est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Hepatocyte nuclear factor 1-alpha(HNF1A) detection. Tested with WB in Human,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Hepatocyte nuclear factor 1-alpha(HNF1A) detection. Tested with WB in Human,Rat.
Gene Name: HNF1 homeobox A
Protein Name: Hepatocyte nuclear factor 1-alpha

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HNF1 recombinant protein (Position: A431-Q631). Human HNF1 shares 93% and 92% amino acid (aa) sequences identity with mouse and rat HNF1, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for HNF1 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-HNF1A (ABIN3042451)

Dai, Cai, Wu, Chen, Han: "Protocatechuic acid inhibits hepatitis B virus replication by activating ERK1/2 pathway and down-regulating HNF4α and HNF1α in vitro." dans: Life sciences, Vol. 180, pp. 68-74, (2017) (PubMed).

Détails sur HNF1A

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Autre désignation: HNF1A (HNF1A Produits)

Synonymes: anticorps HNF-1A, anticorps HNF1, anticorps IDDM20, anticorps LFB1, anticorps MODY3, anticorps TCF-1, anticorps TCF1, anticorps HNF-1a, anticorps AI323641, anticorps HNF1-alpha, anticorps HNF1[a], anticorps Hnf-1, anticorps Hnf1alpha, anticorps Tcf-1, anticorps Tcf1, anticorps HNF-1-alpha, anticorps HNF-1alpha, anticorps LF-B1, anticorps Lfb1, anticorps HNF-1, anticorps HNF1A, anticorps tcf1, anticorps FB1b, anticorps HNF1b, anticorps XLFB1b1, anticorps hnf1-B, anticorps lfb1b, anticorps mody3, anticorps tcf1-B, anticorps tcfb-A, anticorps HNF-1-alpha-A, anticorps HNF-1A-A, anticorps LFB1a1, anticorps TCF-1-A, anticorps XLFB1, anticorps XLFB1b, anticorps hnf1-a, anticorps hnf1a, anticorps hnf1a-a, anticorps hnf1a-b, anticorps hnf1a.L, anticorps tcf1-A, anticorps xx:af244934-22s, anticorps HNF1 homeobox A, anticorps HNF1 homeobox A L homeolog, anticorps HNF1 homeobox A S homeolog, anticorps HNF1 homeobox a, anticorps HNF1A, anticorps Hnf1a, anticorps hnf1a, anticorps hnf1a.L, anticorps hnf1a.S

Sujet: HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A or TCF1, is a human gene. It is mapped to chromosome 12q24.3. The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes. HNF1A can function as a dimer. What's more, deletion of the HNF1A activation domains or interruption of the HNF1-binding sites in the LCT promoter resulted in complete loss of transcriptional activity.

Synonyms: Albumin proximal factor antibody|Hepatic nuclear factor 1 alpha antibody|Hepatic nuclear factor 1 antibody|Hepatic transcription factor 1 alpha antibody|Hepatic transcription factor 1 antibody|Hepatocyte nuclear factor 1-alpha antibody|HNF 1 antibody|HNF 1A antibody|HNF-1-alpha antibody|HNF-1A antibody|HNF1A antibody|HNF1A_HUMAN antibody|Interferon production regulator factor antibody|LF B1 antibody|LF B1 hepatic nuclear factor antibody|LFB 1 antibody|LFB1 antibody|LFB1 hepatic nuclear factor antibody|Liver specific transcription factor LF B1 antibody|Liver specific transcription factor LFB1 antibody|Liver-specific transcription factor LF-B1 antibody|Maturity onset diabetes of the young 3 antibody|MODY 3 antibody|MODY3 antibody|TCF 1 antibody|TCF-1 antibody|TCF1 antibody|Transcription factor 1 antibody|Transcription factor 1 hepatic antibody

ID gène: 6927

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis