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FMO5 anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-FMO5 a été validé pour WB. Il convient pour détecter FMO5 dans des échantillons de Humain.
N° du produit ABIN3042656

Aperçu rapide pour FMO5 anticorps (N-Term) (ABIN3042656)

Antigène

Voir toutes FMO5 Anticorps
FMO5 (Flavin Containing Monooxygenase 5 (FMO5))

Reactivité

  • 42
  • 28
  • 19
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 40
  • 2
Lapin

Clonalité

  • 42
Polyclonal

Conjugué

  • 17
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp FMO5 est non-conjugé

Application

  • 35
  • 16
  • 13
  • 13
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 15
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 77-90, N-Term

    Fonction

    Anti-FMO5 Antibody Picoband®

    Séquence

    DHYPNFMHNA QVLE

    Réactivité croisée (Details)

    No cross-reactivity with other proteins

    Attributs du produit

    Anti-FMO5 Antibody (ABIN3042656). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the N-terminus of human FMO5, different from the related rat sequence by one amino acid, and different from the related mouse sequence by two amino acids.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human
    1. Gelb, B. D., Zhang, J., Cotter, P. D., Gershin, I. F., Desnick, R. J. Physical mapping of the human connexin 40 (GJA5), flavin-containing monooxygenase 5, and natriuretic peptide receptor A genes on 1q21. Genomics 39: 409-411, 1997. 2. Miller, M. M., James, R. A., Richer, J. K., Gordon, D. F., Wood, W. M., Horwitz, K. B.Progesterone regulated expression of flavin-containing monooxygenase 5 by the B-isoform of progesterone receptors: implications for tamoxifen carcinogenicity. J. Clin. Endocr. Metab. 82: 2956-2961, 1997. 3. Overby, L. H., Buckpitt, A. R., Lawton, M. P., Atta-Asafo-Adjei, E., Schulze, J., Philpot, R. M. Characterization of flavin-containing monooxygenase 5(FMO5) cloned from human and guinea pig: evidence that the unique catalytic properties of FMO5 are not confined to the rabbit ortholog. Arch. Biochem. Biophys. 317: 275-284, 1995.

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Agent conservateur

    Thimerosal (Merthiolate), Sodium azide

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    FMO5 (Flavin Containing Monooxygenase 5 (FMO5))

    Autre désignation

    FMO5

    Sujet

    Synonyms: Dimethylaniline monooxygenase [N-oxide-forming] 5,1.14.13.8,Dimethylaniline oxidase 5,Hepatic flavin-containing monooxygenase 5,FMO 5,FMO5,

    Tissue Specificity: Expressed in fetal and adult liver.

    Background: Dimethylaniline monooxygenase[N-oxide-forming] 5 also known as FMO 5 is an enzyme that in humans is encoded by the FMO5 gene. By fluorescence in situ hybridization, this gene was assigned to human chromosome 1q21.1. FMO5 is not an efficient drug-metabolizing enzyme and that it may have an alternative physiologic role. FMO5 transcripts play an important role in progesterone-regulated in breast cancer cells specifically under the control of the progesterone receptor B-isoform.

    Sequence Similarities: Belongs to the FMO family.

    Poids moléculaire

    60 kDa

    UniProt

    P49326
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