Claudin 2 anticorps (AA 38-230)

N° du produit ABIN3042751

Cet anticorps Lapin Polyclonal détecte spécifiquement Claudin 2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain et Rat.Il a été cité dans 1 publication.

Aperçu rapide pour Claudin 2 anticorps (AA 38-230) (ABIN3042751)

Antigène: Claudin 2 (CLDN2)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Claudin 2 anticorps

Épitope: AA 38-230

Fonction: Anti-Claudin 2/CLDN2 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human Claudin 2 shares 92% amino acid (aa) sequence identity with mouse Claudin 2.

Attributs du produit: Anti-Claudin 2/CLDN2 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Claudin 2 recombinant protein (Position: A38-V230). Human Claudin 2 shares 92% amino acid (aa) sequence identity with mouse Claudin 2.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Rat, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Claudin 2 (ABIN3042751)

Cen, Liu, Li, He, Wang, Liu, Liu, Ji: "Alteration in P-glycoprotein at the blood-brain barrier in the early period of MCAO in rats." dans: The Journal of pharmacy and pharmacology, Vol. 65, Issue 5, pp. 665-72, (2013) (PubMed).

Détails sur Claudin 2

Antigène: Claudin 2 (CLDN2)

Autre désignation: CLDN2

Sujet:

Background: Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.

Gene Full Name: claudin 2

Poids moléculaire: 25 kDa

ID gène: 9075

UniProt: P57739

Pathways: Hepatitis C