CMA1 anticorps (AA 22-247)

N° du produit ABIN3042753

Détail du produit anti-CMA1 anticorps

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Épitope: AA 22-247

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CMA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Chymase(CMA1) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Chymase(CMA1) detection. Tested with WB, IHC-P in Human.
Gene Name: chymase 1, mast cell
Protein Name: Chymase

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CMA1 recombinant protein (Position: I22-N247). Human CMA1 shares 75% and 74% amino acid (aa) sequence identity with mouse and rat CMA1, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CMA1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur CMA1

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Autre désignation: CMA1 (CMA1 Produits)

Synonymes: anticorps CYH, anticorps MCT1, anticorps chymase, anticorps MMCP-5, anticorps Mcp-5, anticorps Mcp5, anticorps Mcpt5, anticorps MCP3P, anticorps CMA1, anticorps Chymase, anticorps chymase 1, anticorps chymase 1, mast cell, anticorps chymase-like, anticorps CMA1, anticorps Cma1, anticorps LOC100008644

Sujet: Chymase is a major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. Chymase is mapped to 14q12. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II.

Synonyms: Alpha-chymase antibody|Chymase 1 antibody|Chymase 1 mast cell antibody|Chymase antibody|Chymase, heart antibody|Chymase, mast cell antibody|CMA1 antibody|CMA1_HUMAN antibody|CYH antibody|CYM antibody|EC 3.4.21.39 antibody|Mast cell chymase 1 antibody|Mast cell protease 3 antibody|Mast cell protease 5 antibody|Mast cell protease I antibody|Mast cell protease III antibody|Mcp-5 antibody|MCP3P antibody|Mcpt5 antibody|MGC119890 antibody|MGC119891 antibody|MMCP-5 antibody

ID gène: 1215

UniProt: P23946

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis