CPT1B anticorps (N-Term)

N° du produit ABIN3042757

Cet anticorps Lapin Polyclonal détecte spécifiquement CPT1B dans WB, IHC, IF et IHC (fro). Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour CPT1B anticorps (N-Term) (ABIN3042757)

Antigène: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPT1B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CPT1B anticorps

Épitope: AA 197-226, N-Term

Fonction: Anti-CPT1B Antibody Picoband®

Séquence: DDEEYYRMEL LAKEFQDKTA PRLQKYLVLK

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-CPT1B Antibody Picoband® (ABIN3042757). Tested in IF, IHC, IHC-F, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human CPT1B, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunofluorescence, 5 μg/mL1. Auinger A, Rubin D, Sabandal M, Helwig U, Rüther A, Schreiber S, Foelsch UR, Döring F, Schrezenmeir J. ""A common haplotype of carnitine palmitoyltransferase 1b is associated with the metabolic syndrome"". Br J Nutr, 2013 Mar 14.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CPT1B

Antigène: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Autre désignation: CPT1B

Sujet:

Synonyms: Carnitine O-palmitoyltransferase 1, muscle isoform,CPT1-M,2.3.1.21,Carnitine O-palmitoyltransferase I, muscle isoform,CPT I,CPTI-M,Carnitine palmitoyltransferase 1B,Carnitine palmitoyltransferase I-like protein,CPT1B,KIAA1670,

Tissue Specificity: Strong expression in heart and skeletal muscle. No expression in liver and kidney.

Background: CPT1B is located on 22q13.33. The protein encoded by this gene, a member of the carnitine/ choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.

Sequence Similarities: Belongs to the carnitine/choline acetyltransferase family.

Poids moléculaire: 88 kDa

ID gène: 1375

UniProt: Q92523

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process