CREB3L1 anticorps (AA 1-204)

N° du produit ABIN3042759

Cet anticorps anti-CREB3L1 est un anticorps Lapin Polyclonal détectant CREB3L1 dans WB. Adapté pour Humain.

Aperçu rapide pour CREB3L1 anticorps (AA 1-204) (ABIN3042759)

Antigène: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREB3L1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CREB3L1 anticorps

Épitope: AA 1-204

Fonction: Anti-CREB3L1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-CREB3L1 Antibody Picoband® (ABIN3042759). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CREB3L1 recombinant protein (Position: M1-M204). Human CREB3L1 shares 93.6% and 93.1% amino acid (aa) sequence identity with mouse and rat CREB3L1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human
1. Denard B, Lee C, Ye J. ""Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1"". Elife, 2012 Dec 18. 2. Mellor P, Deibert L, Calvert B, Bonham K, Carlsen SA, Anderson DH. ""CREB3L1 is a metastasis suppressor that represses expression of genes regulating metastasis, invasion, and angiogenesis"". Mol Cell Biol, 2013 Dec.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CREB3L1

Antigène: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Autre désignation: CREB3L1

Sujet:

Synonyms: Cyclic AMP-responsive element-binding protein 3-like protein 1,cAMP-responsive element-binding protein 3-like protein 1,Old astrocyte specifically-induced substance,OASIS,Processed cyclic AMP-responsive element-binding protein 3-like protein 1,CREB3L1,OASIS,PSEC0238,

Tissue Specificity: Expressed in several tissues, with highest levels in pancreas and prostate. Expressed at relatively lower levels in brain. .

Background: CREB3L1, known as Cyclic AMP-responsive element-binding protein 3-like protein 1, is mapped to 11p11.2. The protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box-B elements.

Sequence Similarities: Belongs to the bZIP family. ATF subfamily.

Poids moléculaire: 57 kDa

ID gène: 90993

Pathways: Thyroid Hormone Synthesis, Chromatin Binding