Interleukin 17a anticorps (AA 26-158)
Aperçu rapide pour Interleukin 17a anticorps (AA 26-158) (ABIN3042799)
Antigène
Voir toutes Interleukin 17a (IL17A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 26-158
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Fonction
- Anti-IL17/IL17A Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Attributs du produit
- Anti-IL17/IL17A Antibody (ABIN3042799). Tested in ELISA, WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived mouse IL-17 recombinant protein (Position: A26-A158).
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Isotype
- IgG
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Indications d'application
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ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Mouse
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify Carrier Free or No BSA in your order note.
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Agent conservateur
- Sodium azide, Without preservative
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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: "Imbalances of Th17 and Treg cells and their respective cytokines in COPD patients by disease stage." dans: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 5324-9, (2015) (PubMed).
: "Th17 cells are associated with the Th1/Th2?cell balance during Echinococcus multilocularis infection." dans: Molecular medicine reports, Vol. 10, Issue 1, pp. 236-40, (2014) (PubMed).
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: "Imbalances of Th17 and Treg cells and their respective cytokines in COPD patients by disease stage." dans: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 5324-9, (2015) (PubMed).
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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Autre désignation
- IL17A
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Sujet
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Synonyms: Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,Il17a,Ctla8, Il17,
Tissue Specificity: Restricted to a subset of activated T-cells. .
Background: Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Sequence Similarities: Belongs to the immunoglobulin superfamily. CEA family.
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Poids moléculaire
- 30 kDa
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UniProt
- Q62386
Antigène
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