Interleukin 17a anticorps (AA 26-158)

N° du produit ABIN3042799

Détail du produit anti-Interleukin 17a anticorps

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Épitope: AA 26-158

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Interleukin 17a est non-conjugé

Application: ELISA, Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Interleukin-17A(IL17A) detection. Tested with WB, ELISA in Mouse.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Interleukin-17A(IL17A) detection. Tested with WB, ELISA in Mouse.
Gene Name: interleukin 17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8
Protein Name: Interleukin-17A(IL-17/IL-17A)

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse IL-17 recombinant protein(Position: A26-A158).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Species: Mouse
ELISA: Concentration: 0.1-0.5 μg/mL, Species: Mouse

Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-Interleukin 17a (ABIN3042799)

Li, Pan, Qiu: "Imbalances of Th17 and Treg cells and their respective cytokines in COPD patients by disease stage." dans: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 5324-9, (2015) (PubMed).

Ma, Wang, Zhao, Pang, Zhang, Jiang, Liu, Mamuti, Wen, Ding: "Th17 cells are associated with the Th1/Th2?cell balance during Echinococcus multilocularis infection." dans: Molecular medicine reports, Vol. 10, Issue 1, pp. 236-40, (2014) (PubMed).

Détails sur Interleukin 17a

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Autre désignation: IL17A (IL17A Produits)

Synonymes: anticorps CTLA8, anticorps IL-17, anticorps IL-17A, anticorps IL17, anticorps Ctla-8, anticorps Ctla8, anticorps Il17, anticorps ChIL-17, anticorps IL-17F, anticorps IL17A, anticorps CTLA-8, anticorps interleukin 17A, anticorps IL17A, anticorps Il17a

Sujet: IL-17(Interleukin-17), originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993, is the founding member of a group of cytokines called the IL-17 family. Known as CTLA8 in rodents, IL-17 shows high homology to viral IL-17 encoded by an open reading frame of the T-lymphotropic rhadinovirus Herpesvirus saimiri. Mouse IL-17 shares 85 % amino acid sequence homology with rat. Interleukin 17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation, similar to Interferon gamma. IL-17 is produced by T-helper cells and is induced by IL-23 which results in destructive tissue damage in delayed-type reactions. Interleukin 17 as a family functions as a proinflammatory cytokine that responds to the invasion of the immune system by extracellular pathogens and induces destruction of the pathogen's cellular matrix. Interleukin 17 acts synergistically with tumor necrosis factor and interleukin-1. To elicit its functions, IL-17 binds to a type I cell surface receptor called IL-17R of which there are at least three variants IL17RA, IL17RB, and IL17RC.

Synonyms: CTLA 8 antibody|CTLA-8 antibody|CTLA8 antibody|Cytotoxic T lymphocyte associated antigen 8 antibody|Cytotoxic T lymphocyte associated protein 8 antibody|Cytotoxic T lymphocyte associated serine esterase 8 antibody|Cytotoxic T-lymphocyte-associated antigen 8 antibody|IL 17A antibody|IL-17 antibody|IL-17A antibody|IL17 antibody|IL17A antibody|Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody|Interleukin 17A antibody|Interleukin-17A antibody|Interleukin17 antibodyInter|leukin17A antibody|OTTHUMP00000016597 antibody|OTTMUSP00000046003 antibody

UniProt: Q62386