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LI Cadherin anticorps (C-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement LI Cadherin dans WB. Il présente une réactivité envers Humain.
N° du produit ABIN3042838

Aperçu rapide pour LI Cadherin anticorps (C-Term) (ABIN3042838)

Antigène

Voir toutes LI Cadherin Anticorps
LI Cadherin

Reactivité

  • 85
  • 10
  • 8
  • 7
Humain

Hôte

  • 50
  • 33
  • 4
Lapin

Clonalité

  • 55
  • 27
  • 3
Polyclonal

Conjugué

  • 46
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp LI Cadherin est non-conjugé

Application

  • 50
  • 44
  • 31
  • 25
  • 23
  • 10
  • 9
  • 5
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 37
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 686-699, C-Term

    Fonction

    Anti-LI-Cadherin-17 CDH17-Antibody Picoband®

    Séquence

    LIFEATDDDQ HLFR

    Réactivité croisée (Details)

    No cross-reactivity with other proteins

    Attributs du produit

    Anti-LI-Cadherin-17 CDH17-Antibody (ABIN3042838). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the C-terminus of human LI Cadherin.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human
    1. Dantzig, A. H., Hoskins, J., Tabas, L. B., Bright, S., Shepard, R. L., Jenkins, I. L., Duckworth, D. C., Sportsman, J. R., Mackensen, D., Rosteck, P. R., Jr., Skatrud, P. L. Association of intestinal peptide transport with a protein related to the cadherin superfamily. cience 264: 430-433, 1994. 2. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998.

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Agent conservateur

    Thimerosal (Merthiolate), Sodium azide

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    LI Cadherin

    Autre désignation

    CDH17

    Sujet

    Synonyms: Cadherin-17,Intestinal peptide-associated transporter HPT-1,Liver-intestine cadherin,LI-cadherin,CDH17,

    Tissue Specificity: Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. .

    Background: Cadherin-17, also known as HPT1 or CDH16 is a protein that in humans is encoded by the CDH17 gene. By somatic cell hybrid analysis and fluorescence in situ hybridization, CDH17 gene is mapped to 8q22.1. This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.

    Sequence Similarities: Contains 7 cadherin domains.

    Poids moléculaire

    92 kDa

    UniProt

    Q12864
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