CDC37 anticorps (C-Term)
Aperçu rapide pour CDC37 anticorps (C-Term) (ABIN3042880)
Antigène
Voir toutes CDC37 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- Anti-Cdc37 Antibody
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Séquence
- DPLLEAVPKT GDEKDV
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- different from the related mouse sequence by two amino acids,and from the related rat sequence by three amino acids.
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Attributs du produit
- Anti-Cdc37 Antibody. Tested in WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human Cdc37, different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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Agent conservateur
- Thimerosal (Merthiolate), Sodium azide
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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: "The effect of 5'-adenylic acid on hepatic proteome of mice radiated by 60Co γ-ray." dans: International journal of molecular sciences, Vol. 15, Issue 1, pp. 186-202, (2014) (PubMed).
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- CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))
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Autre désignation
- CDC37
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Sujet
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Background: Hsp90 co-chaperone Cdc37, also called P50CDC37 is a protein that in humans is encoded by the CDC37 gene. The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This gene is mapped to 19p13.2. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is though to play a critical role in ing Hsp90 to its target kinases.
Gene Full Name: cell division cycle 37, HSP90 cochaperone
Sequence Similarities: Belongs to the CDC37 family.
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Poids moléculaire
- 44 kDa
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ID gène
- 11140
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UniProt
- Q16543
Antigène
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