CXCR1 anticorps (N-Term)

N° du produit ABIN3042912

Détail du produit anti-CXCR1 anticorps

Antigène: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Épitope: AA 24-38, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 1(CXCR1) detection. Tested with WB, IHC-P in Human.

Séquence: DEDYSPCMLE TETLN

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 1(CXCR1) detection. Tested with WB, IHC-P in Human.
Gene Name: chemokine(C-X-C motif) receptor 1
Protein Name: C-X-C chemokine receptor type 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR1(24-38aa DEDYSPCMLETETLN).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CXCR1

Antigène: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Autre désignation: CXCR1 (CXCR1 Produits)

Synonymes: anticorps C-C, anticorps C-C-CKR-1, anticorps CD128, anticorps CD181, anticorps CDw128a, anticorps CKR-1, anticorps CMKAR1, anticorps IL8R1, anticorps IL8RA, anticorps IL8RBA, anticorps Il8ra, anticorps CXCR-1, anticorps IL-8RA, anticorps CXCR2, anticorps IL8RB, anticorps cxcr1, anticorps cxcr2, anticorps C-X-C motif chemokine receptor 1, anticorps chemokine (C-X-C motif) receptor 1, anticorps C-X-C chemokine receptor type 1, anticorps C-X-C motif chemokine receptor 1 S homeolog, anticorps CXCR1, anticorps Cxcr1, anticorps LOC100461947, anticorps cxcr1.S

Sujet: CXCR1(Chemokine,CXC Motif, Receptor 1), also known as IL8RA or IL8R1, is a chemokine receptor. IL8RA is its human gene. Morris et al.(1992) mapped the IL8RA gene to chromosome 2q35. Hartl et al.(2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic mechanism in CF and other neutrophilic airway diseases. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA(GRO) with a low affinity.

Synonyms: C C antibody|C C CKR 1 antibody|C-X-C chemokine receptor type 1 antibody|CCCKR1 antibody|CD 181 antibody|CD128 antibody|CD181 antibody|CD181 antigen antibody|CDw128a antibody|Chemokine(C X C motif) receptor 1 antibody|Chemokine(C X C) receptor 1 antibody|Chemokine receptor 1 antibody|CKR 1 antibody|CMKAR1 antibody|CXC-R1 antibody|CXCR 1 antibody|CXCR-1 antibody|CXCR1 antibody|CXCR1_HUMAN antibody|High affinity interleukin 8 receptor A antibody|High affinity interleukin-8 receptor A antibody|IL 8 receptor type 1 antibody|IL 8R A antibody|IL-8 receptor type 1 antibody|IL-8R A antibody|IL8 receptor antibody|IL8 receptor type 1 antibody|IL8R1 antibody|IL8RA antibody|IL8RBA antibody|Interleukin 8 receptor alpha antibody|Interleukin 8 receptor type 1 antibody|Interleukin 8 receptor type A antibody

UniProt: P25024

Pathways: cAMP Metabolic Process