Cullin 3 anticorps (Middle Region)

N° du produit ABIN3042989

Détail du produit anti-Cullin 3 anticorps

Antigène: Cullin 3 (CUL3)

Épitope: AA 426-444, Middle Region

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cullin 3 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Cullin-3(CUL3) detection. Tested with WB in Human,Mouse,Rat.

Séquence: DVFERYYKQH LARRLLTNK

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Cullin-3(CUL3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: cullin 3
Protein Name: Cullin-3

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Cullin 3(426-444aa DVFERYYKQHLARRLLTNK), identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for CUL3 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Cullin 3

Antigène: Cullin 3 (CUL3)

Autre désignation: CUL3 (CUL3 Produits)

Synonymes: anticorps CUL-3, anticorps Cullin-3, anticorps CUL-3-A, anticorps Cullin-3-A, anticorps cul3, anticorps cul3a, anticorps CUL-3-B, anticorps Cullin-3-B, anticorps cul3b, anticorps wu:fc37e01, anticorps CUL3, anticorps ATCUL3, anticorps ATCUL3A, anticorps CUL3A, anticorps T24P13.25, anticorps cullin 3, anticorps cullin 3A, anticorps PHA2E, anticorps AI467304, anticorps AW146203, anticorps mKIAA0617, anticorps cullin 3, anticorps cullin 3 L homeolog, anticorps cullin 3 S homeolog, anticorps cullin-3, anticorps Cullin-3 (CUL-3), anticorps cullin 3a, anticorps CULlin, anticorps CUL3, anticorps cul3, anticorps cul3.L, anticorps cul3.S, anticorps PTRG_11586, anticorps Smp_117580, anticorps cul3a, anticorps Cul3, anticorps cul-3

Sujet: Cullin-3(Cul 3), is a protein that in humans is encoded by the CUL3 gene. Kipreos et al.(1996) identified a conserved gene family, designated cullins, with at least 5 members in nematodes, 6 in humans, and 3 in S. cerevisiae. Human CUL3 is an ortholog of nematode cul3. Hartz(2012) mapped the CUL3 gene to chromosome 2q36.2 based on an alignment of the CUL3 sequence with the genomic sequence(GRCh37). Sumara et al.(2007) found that KLHL9, KLHL13, and CUL3 interacted directly in a 370-kD protein complex in HeLa cell lysates. Rondou et al.(2008) showed that interaction between KLHL12 and the CUL3 ubiquitin ligase complex directed ubiquitination of dopamine receptor D4(DRD4). KLHL12 interacted directly with CUL3 and with the polymorphic intracellular loop-3 of D4. By immunoprecipitation analysis of HeLa cells and HCT116 human colon carcinoma cells expressing epitope-tagged proteins, Kigoshi et al.(2011) showed that KLHL7 interacted with CUL3 and ROC1(RBX1).

Synonyms: CUL 3 antibody|Cul-3 antibody|CUL3 antibody|CUL3_HUMAN antibody|Cullin-3 antibody|Cullin3 antibody|KIAA0617 antibody

UniProt: Q13618

Pathways: M Phase