HSC70 Interacting Protein HIP anticorps (N-Term)

N° du produit ABIN3042991

Détail du produit anti-HSC70 Interacting Protein HIP anticorps

Antigène: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Épitope: AA 1-19, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSC70 Interacting Protein HIP est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Hsc70-interacting protein(ST13) detection. Tested with WB in Human.

Séquence: MDPRKVNELR AFVKMCKQD

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Hsc70-interacting protein(ST13) detection. Tested with WB in Human.
Gene Name: suppression of tumorigenicity 13(colon carcinoma)(Hsp70 interacting protein)
Protein Name: Hsc70-interacting protein

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human ST13(1-19aa MDPRKVNELRAFVKMCKQD), different from the related rat and mouse sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HSC70 Interacting Protein HIP

Antigène: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Autre désignation: ST13 (ST13 Produits)

Synonymes: anticorps CG32789, anticorps Dmel\\CG32789, anticorps anon-EST:fe1A9, anticorps 1110007I03Rik, anticorps 3110002K08Rik, anticorps AW555194, anticorps HIP, anticorps HOP, anticorps HSPABP, anticorps HSPABP1, anticorps PRO0786, anticorps SNC6, anticorps p48, anticorps AAG2, anticorps FAM10A1, anticorps FAM10A4, anticorps P48, anticorps Hsc/Hsp70-interacting protein, anticorps suppression of tumorigenicity 13, anticorps ST13, Hsp70 interacting protein, anticorps suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein), anticorps HIP, anticorps St13, anticorps ST13

Sujet: ST13(Suppression of Tumorigenicity 13), also known as P48 or HIP, is a protein that in humans is encoded by the ST13 gene. ST13 is an abundant, highly conserved protein that binds the major cytosolic chaperones heat-shock protein 70-kD(HSP70) and HSP90 during an intermediate stage of steroid receptor assembly, but is absent from the mature receptor complex. Zhang et al.(1998) mapped the ST13 gene to chromosome 22q13 by fluorescence in situ hybridization. They noted that colorectal, breast, and ovarian carcinomas frequently show loss of heterozygosity at this site. Using a yeast 2-hybrid assay, Hohfeld et al.(1995) showed that rat Hip bound Hsc70(HSPA8). One Hip oligomer bound the ATPase domains of at least 2 Hsc70 Molecules, and binding was dependent on activation of the Hsc70 ATPase by Hsp40(DNAJB1). Hip stabilized the ADP-bound form of Hsc70, which had a high affinity for a test protein substrate. Hohfeld et al.(1995) concluded that HIP contributes to interactions of HSC70 with target proteins through its own chaperone activity.

Synonyms: AAG 2 antibody|AAG2 antibody|Aging associated protein 2 antibody|F10A1_HUMAN antibody|FAM10A1 antibody|FAM10A4 antibody|FLJ27260 antibody|Heat shock 70kD protein binding protein antibody|HIP antibody|HOP antibody|Hsc70 interacting protein antibody|Hsc70-interacting protein antibody|Hsp70 interacting protein antibody|HSPABP 1 antibody|HSPABP antibody|HSPABP1 antibody|MGC129952 antibody|OTTHUMP00000028873 antibody|P48 antibody|PRO0786 antibody|Progesterone receptor associated p48 protein antibody|Progesterone receptor-associated p48 protein antibody|Protein FAM10A1 antibody|Putative tumor suppressor ST13 antibody|Renal carcinoma antigen NY REN 33 antibody|Renal carcinoma antigen NY-REN-33 antibody|SNC 6 antibody|SNC6 antibody|ST 13 antibody|ST13 antibody|Suppression of tumorigenicity 13 antibody|Suppression of tumorigenicity 13(colon carcinoma) antibody|Suppression of tumorigenicity 13 protein antibody|Suppression of tumorigenicity protein 13 antibody

UniProt: P50502