CCR4 anticorps (Middle Region)

N° du produit ABIN3043172

Il existe 1 publication pour ce produit. L’anticorps anti-CCR4 Polyclonal Lapin est utilisé pour la détection de CCR4 dans des échantillons de Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour CCR4 anticorps (Middle Region) (ABIN3043172)

Antigène: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CCR4 anticorps

Épitope: Middle Region

Fonction: Anti-C-C chemokine receptor type 4 CCR4 Antibody

Séquence: SYTQSTVDHD FRDAL

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related rat sequence.

Attributs du produit: Anti-C-C chemokine receptor type 4 CCR4 Antibody. Tested in WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of mouse CCR4, identical to the related rat sequence.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse, Rat

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CCR4 (ABIN3043172)

Zhao, Bu, Wang, Ma, Ma: "GEC-derived SFRP5 inhibits Wnt5a-induced macrophage chemotaxis and activation." dans: PLoS ONE, Vol. 9, Issue 1, pp. e85058, (2014) (PubMed).

Détails sur CCR4

Antigène: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Autre désignation: CCR4

Sujet:

Background: CCR4,C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194 (cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines. The CCR4 gene is mapped to chromosome 3. Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Gene Full Name: C-C motif chemokine receptor 4

Sequence Similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Poids moléculaire: 41 kDa

ID gène: 12773

UniProt: P51680