CA3 anticorps (N-Term)

N° du produit ABIN3043222

Cet anticorps Lapin Polyclonal détecte spécifiquement CA3 dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CA3 anticorps (N-Term) (ABIN3043222)

Antigène: CA3 (Carbonic Anhydrase III (CA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CA3 anticorps

Épitope: AA 2-20, N-Term

Fonction: Anti-Carbonic Anhydrase III/CA3 Antibody Picoband®

Séquence: AKEWGYASHN GPDHWHELF

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Carbonic Anhydrase III/CA3 Antibody (ABIN3043222). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human CA3, different from the related mouse and rat sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
1. Edwards, Y. H., Lloyd, J. C., Parkar, M., Povey, S.The gene for human muscle specific carbonic anhydrase (CAIII) is assigned to chromosome 8.Ann. Hum. Genet. 50: 41-47, 1986. 2. Heath, R., Carter, N. D., Jeffery, S., Edwards, R. J., Watts, D. C., Watts, R. L.Evaluation of carrier detection of Duchenne muscular dystrophy using carbonic anhydrase III and creatine kinase.Am. J. Med. Genet. 21: 291-296, 1985. 3. Wade, R., Gunning, P., Eddy, R., Shows, T., Kedes, L.Nucleotide sequence, tissue-specific expression, and chromosome location of human carbonic anhydrase III: the human CAIII gene is located on the same chromosome as the closely linked CAI and CAII genes.Proc. Nat. Acad. Sci. 83: 9571-9575, 1986.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CA3

Antigène: CA3 (Carbonic Anhydrase III (CA3))

Autre désignation: CA3

Sujet:

Synonyms: Carbonic anhydrase 3,4.2.1.1,Carbonate dehydratase III,Carbonic anhydrase III,CA-III,CA3,

Tissue Specificity: Muscle specific.

Background: Carbonic anhydrase III (CA3) is an enzyme that in humans is encoded by the CA3 gene. CA3 is a member of a multigene family (at least six separate genes are known) that encode carbonic anhydrase isozymes. The gene spans 10.3 kb and contains seven exons and six introns. Using a cDNA clone of the CA3 gene in the study of human-rodent hybrids, the gene was mapped to chromosome 8 which carries a cluster of CA genes. CA3 is found in high concentration in muscle. CA3 is used in conjunction with creatine kinase detection of the carrier state for Duchenne muscular dystrophy.

Sequence Similarities: Belongs to the Bcl-2 family.

Poids moléculaire: 23 kDa

UniProt: P07451