STXBP2 anticorps (N-Term)

N° du produit ABIN3043304

L’anticorps anti-STXBP2 Polyclonal produit chez le Lapin a été validé pour WB, IF, ICC et FACS. Il convient pour la détection de STXBP2 dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour STXBP2 anticorps (N-Term) (ABIN3043304)

Antigène: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STXBP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-STXBP2 anticorps

Épitope: AA 184-215, N-Term

Fonction: Anti-STXBP2 Antibody

Séquence: QEYPAIRYRK GPEDTAQLAH AVLAKLNAFK AD

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-STXBP2 Antibody (ABIN3043304). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human STXBP2, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur STXBP2

Antigène: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Autre désignation: STXBP2

Sujet:

Synonyms: Syntaxin-binding protein 2,Protein unc-18 homolog 2,Unc18-2,Protein unc-18 homolog B,Unc-18B,STXBP2,UNC18B,

Tissue Specificity: Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.

Background: Syntaxin-binding protein 2, also known as UNC18B, is a protein that in humans is encoded by the STXBP2 gene. The STXBP2 gene is mapped to human chromosome 19p13.3-p13.2 and to the proximal arm of mouse chromosome 8. And this gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Additionally, UNC18B is expressed predominantly as a 2.4-kb message in placenta, lung, liver, kidney, and pancreas, as well as in peripheral blood lymphocytes. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Poids moléculaire: 66 kDa

ID gène: 6813

UniProt: Q15833

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis