SERPINB2 anticorps (AA 1-180)

N° du produit ABIN3043329

Détail du produit anti-SERPINB2 anticorps

Antigène: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Épitope: AA 1-180

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Plasminogen activator inhibitor 2(SERPINB2) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Plasminogen activator inhibitor 2(SERPINB2) detection. Tested with WB, IHC-P in Human.
Gene Name: serpin peptidase inhibitor, clade B (ovalbumin), member 2
Protein Name: Plasminogen activator inhibitor 2

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SerpinB2 recombinant protein (Position: M1-K180). Human SerpinB2 shares 70% and 66% amino acid (aa) sequence identity with mouse and rat SerpinB2, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SerpinB2 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur SERPINB2

Antigène: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Autre désignation: SERPINB2 (SERPINB2 Produits)

Synonymes: anticorps HsT1201, anticorps PAI, anticorps PAI-2, anticorps PAI2, anticorps PLANH2, anticorps SERPINB2, anticorps Planh2, anticorps ovalbumin, anticorps Pai2a, anticorps serpin family B member 2, anticorps serpin peptidase inhibitor, clade B (ovalbumin), member 2, anticorps serine (or cysteine) peptidase inhibitor, clade B, member 2, anticorps SERPINB2, anticorps Serpinb2

Classe de substances: Amino Acid

Sujet: SERPINB2 is also known as PAI or PAI2. Plasminogen activator inhibitor-2 (placental PAI) is acoagulation factor that inactivates tPA and urokinase. It is present in most cells, especially monocytes/macrophages. PAI-2 exists in two forms, a 60- kDa extracellular glycosylated form and a 43- kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosisduring pregnancy. The majority of expressed PAI-2 remains unsecreted due to the presence of an inefficient internal signal peptide.

Synonyms: HsT1201 antibody|Monocyte Arg serpin antibody|Monocyte Arg-serpin antibody|Monocyte Arginine-serpin antibody|Monocyte-derived plasminogen activator inhibitor antibody|PAI antibody|PAI-2 antibody|PAI2 antibody|PAI2_HUMAN antibody|Placental plasminogen activator inhibitor antibody|PLANH2 antibody|Plasminogen activator inhibitor 2 antibody|plasminogen activator inhibitor, type 2 antibody|plasminogen activator inhibitor, type II (arginine-serpin) antibody|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 antibody|Serpin B2 antibody|serpin peptidase inhibitor, clade B (ovalbumin), member 2 antibody|Serpinb2 antibody|Urokinase inhibitor antibody

ID gène: 5055

UniProt: P05120

Pathways: Autophagy