PKC eta anticorps (AA 30-389)

N° du produit ABIN3043361

Détail du produit anti-PKC eta anticorps

Antigène: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Épitope: AA 30-389

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC eta est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Protein kinase C eta type(PRKCH) detection. Tested with WB in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Protein kinase C eta type(PRKCH) detection. Tested with WB in Human.
Gene Name: protein kinase C, eta
Protein Name: Protein kinase C eta type

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PKC eta recombinant protein (Position: R30-D389). Human PKC eta shares 96.7% and 96.1% amino acid (aa) sequence identity with mouse and rat PKC eta, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-PKC eta (ABIN3043361)

Gan, Wang, Zhao, Wu, Yang, Peng: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." dans: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).

Détails sur PKC eta

Antigène: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Autre désignation: PRKCH (PRKCH Produits)

Synonymes: anticorps PKC-L, anticorps PKCL, anticorps PRKCL, anticorps nPKC-eta, anticorps Pkch, anticorps pkc-eta, anticorps PRKCH, anticorps prkch, anticorps si:ch211-212g7.5, anticorps zgc:172124, anticorps protein kinase C eta, anticorps protein kinase C, eta, anticorps protein kinase C eta L homeolog, anticorps protein kinase C, eta, b, anticorps protein kinase C, eta, a, anticorps protein kinase C epsilon, anticorps PRKCH, anticorps Prkch, anticorps prkch.L, anticorps prkchb, anticorps prkcha, anticorps prkch, anticorps PRKCE

Sujet: PRKCH is also known as PKC eta. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Also, PKC family members serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. And it is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

Synonyms: KPCL_HUMAN antibody|MGC 5363 antibody|MGC26269 antibody|MGC5363 antibody|nPKC eta antibody| nPKC-eta antibody|PKC h antibody|PKC L antibody|PKC-L antibody|PKCh antibody|PKCL antibody| Prkch antibody|PRKCL antibody|Protein kinase C eta antibody|Protein kinase C eta type antibody

ID gène: 5583

UniProt: P24723

Pathways: Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling