MTDH anticorps (AA 101-270)

N° du produit ABIN3043367

Détail du produit anti-MTDH anticorps

Antigène: MTDH (Metadherin (MTDH))

Épitope: AA 101-270

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTDH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Protein LYRIC(MTDH) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Protein LYRIC(MTDH) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: metadherin
Protein Name: Protein LYRIC

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human LYRIC recombinant protein (Position: D101-Q270). Human LYRIC shares 94% amino acid (aa) sequence identity with both mouse and rat LYRIC.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for LYRIC is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur MTDH

Antigène: MTDH (Metadherin (MTDH))

Autre désignation: MTDH (MTDH Produits)

Synonymes: anticorps MGC75963, anticorps 2610103J23Rik, anticorps 3D3, anticorps 3D3/Lyric, anticorps AEG-1, anticorps AV353288, anticorps D8Bwg1112e, anticorps Lyric, anticorps AEG1, anticorps LYRIC, anticorps LYRIC/3D3, anticorps metadherin, anticorps mtdh, anticorps MTDH, anticorps Mtdh

Sujet: MTDH (Metadherin), also known as protein LYRIC or astrocyte elevated gene-1 protein (AEG-1) is a protein that in humans is encoded by the MTDH gene. AEG-1 is involved in HIF-1alpha mediated angiogenesis. AEG-1 also interacts with SND1 and involved in RNA-induced silencing complex (RISC) and plays very important role in RISC and miRNA functions. AEG-1 induces an oncogene called Late SV40 factor (LSF/TFCP2) which is involved in thymidylate synthase (TS) induction and DNA biosynthesis synthesis. Late SV40 factor (LSF/TFCP2) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP9). AEG-1 acts as an oncogene in melanoma, malignant glioma, breast cancer and hepatocellular carcinoma. It is highly expressed in these cancers and helps in progression and development of these cancers. It is induced by c-Myc oncogene and plays very important role in anchorage independent growth of cancer cells.

Synonyms: 3D3 antibody|3D3/LYRIC antibody|AEG 1 antibody|AEG-1 antibody|AEG1 antibody|Astrocyte elevated gene 1 antibody|Astrocyte elevated gene-1 protein antibody|LYRIC antibody|LYRIC/3D3 antibody|LYRIC_HUMAN antibody|Lysine rich CEACAM1 associated protein antibody|Lysine rich CEACAM1 co isolated protein antibody|Lysine-rich CEACAM1 co-isolated protein antibody|Metadherin antibody|Metastasis adhesion protein antibody|MTDH antibody|Protein LYRIC antibody

ID gène: 92140

Pathways: Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization